FDA-authorised indications may perhaps range for various oxycodone kinds and strengths. Examine the solution package deal insert for indications and usage for every solution. 

Significant adverse effects which include respiratory despair is usually dealt with Using the opioid antagonist naloxone.[Ref]

the each day dose, potency and qualities of an entire agonist or combined agonist/antagonist the individual continues to be using Beforehand.

Choose precisely the amount of money prescribed by your physician. Don't take much more than that, even though your agony isn't completely managed. Discuss with your physician In the event your agony degree alterations.

You should not use OxyContin Except that you are previously working with an identical opioid medicine and are tolerant to it.

Tend not to abruptly discontinue oxycodone HCl in patients who could be physically depending on opioids. Fast discontinuation of opioid analgesics in sufferers who will be physically dependent on opioids has resulted in major withdrawal indicators, uncontrolled pain, and suicide.

Propulsive peristaltic waves within the colon are lowered, while tone may very well be greater to The purpose of spasm, causing constipation. Other opioid-induced outcomes could incorporate a discount in biliary and pancreatic secretions, spasm of sphincter of Oddi, and transient elevations in serum amylase.

Should you be amongst the ages of eighteen and sixty, choose no other medication or haven't any other healthcare disorders, Unwanted side effects you are more likely to working experience consist of:

People ought to realize the hazards of lifestyle-threatening respiratory despair, and become knowledgeable concerning when this risk is finest; clients and caregivers ought to be instructed to receive emergency help without delay if too much drug is taken or if breathing troubles occur.

Take into consideration prescribing naloxone, depending on the patient's hazard things for overdose, for example concomitant usage of CNS depressants, a record of opioid use disorder, or prior opioid overdose. The existence of possibility factors for overdose must not protect against the appropriate management of pain in any specified client.

Constantly consult your Health care provider to guarantee the data shown on this web site relates to your personal instances.

Lengthy-expression use of opioid medication may influence fertility (power to have young children) in Males or Women of all ages. It's not at all known whether opioid consequences on fertility are everlasting.

Carbon dioxide (CO2) retention from opioid-induced respiratory depression can exacerbate the sedating consequences of opioids. Though severe, lifetime-threatening, or deadly respiratory depression can arise Anytime in the course of using oxycodone HCl, the risk is greatest through the initiation of therapy or next a dosage raise. Watch sufferers closely for respiratory melancholy, Specifically throughout the to start with 24 to 72 hrs of initiating therapy with and subsequent dosage will increase of oxycodone HCl.

Utilizing OxyContin with medicines that are CYP3A4 inhibitors or discontinuation of CYP3A4 inducers can result in a lethal overdose of oxycodone. Opioid medication can connect with many other medications and result in perilous Unintended effects or Loss of life. Be certain your health care provider is aware read more of if In addition, you use: